Familial koilonychia

Very rare familial spoon nails (Koilonychia)

An 85yearold woman presented with platonychia and koilonychia (spoonshaped nails) of the fingers and toes which were present since her early childhood (Figure 1A and B). On physical examination, all her fingernails were spoonshaped with rough and darkened distal edges. Her toenails were thin and flat, except for the nails of the big toes, which exhibited the same abnormalities as the fingernail...

A syndrome of leukonychia, koilonychia and multiple pilar cysts.

© 2015 The Authors. doi: 10.2340/00015555-1893 Journal Compilation © 2015 Acta Dermato-Venereologica. ISSN 0001-5555 Familial leuconychia with pilar cysts is a rare autosomal dominant condition, previously reported in 6 families. The molecular basis of the disorder is unknown. We report a family of 5 generations with leuconychia, koilonychia and multiple pilar cysts segregating as an autosomal ...

Koilonychia in a patient with subacute iron-deficiency anemia.

A 53-year-old woman who had been taking aspirin to prevent ischemic stroke visited our hospital due to general malaise. A physical examinations revealed pallor of the conjunctiva and koilonychia (spoon-shaped nails) (Picture A), although she had not exhibited anemia or koilonychia three months earlier. Laboratory studies demonstrated severe microcytic anemia (hemoglobin, 5.9 g/dL; mean corpuscu...

LE PLACEMENT FAMILIAL

Familial hypercholesterolemia: a case report

Abstract Familial hypercholesterolemia (FH) is a hereditary dislipidemia. Patients present with extremely high level of low-density lipoprotein cholesterol (LDL-C), which is due to mutation in the gene of LDL receptor. Homozygous patients (HoFH) whose incidence is 1 in 1.000.000 are at high risk of premature aortic valve stenosis, and coronary artery atherosclerosis. In homozygous individual...